Challenges continue for training and safety with ultrasound-guided peripheral catheter insertions and procedural performance in clinical practice. Issues of implementation of disinfection, standardized probe protection, application of aseptic non touch technique ANTT, and establishing effective training with follow-up all require attention to apply changing recommendations and update policies. This discussion will blend current recommendations and options, along with real-life applications and stories describing clinical usage specific to a children's hospital and emergency department. Come and learn about ultrasound-guided PIV applications, new developments and methods to standardize your programs.